Tadalafil is an improved and advanced PDE5 inhibitor that FDA approves for treating erectile dysfunction. With an onset of action of 30 minutes, this ED pill's effects last about 36 hours. Marketed under various brands, the muscle-relaxing property of Tadalafil is also beneficial in improving the signs of Benign Prostatic Hyperplasia (BPH) and Pulmonary Arterial Hypertension (PAH).
Australia (AU)- S4 (Prescription only)
Canada- Prescription only
USA- Prescription only
|FDA approval||Yes, In 2003|
|Therapeutic Class||Sex stimulants rejuvenators|
|Action Class||Phosphodiesterase-V inhibitors|
Tadalafil is a phosphodiesterase type 5 inhibitor (PDE5 inhibitor) medication and an effective Erectile Dysfunction treatment.
Erectile Dysfunction (ED) is an erection disorder in men that causes difficulty in attaining and maintaining an erection.
Along with erectile dysfunction (ED), it treats the symptoms of Benign Prostatic Hyperplasia (BPH), a condition that affects urination. This medication also aids in treating Pulmonary Arterial Hypertension (PAH), a high blood pressure condition affecting the lungs and heart.
Tadalafil is sold under various brands or trade names.
The manufacturer assigns the brand name, whereas the generic name refers to the active ingredient.
Nitric Oxide (NO), released from the nerve terminals and cells, stimulates the combination of cyclic guanosine monophosphate (cGMP). The cGMP is a secondary messenger that enhances the physiological process. It helps muscle relaxation of the corpus cavernosum (spongy tissue surrounding the penis) and widening of blood vessels to the penile region resulting in an erection.
However, the phosphodiesterase type 5 ( PDE5) enzyme breaks down the cGMP accumulation causing erectile issues.
Intaking of Tadalafil helps to stop the breaking of cGMP by inhibiting the PDE5 enzyme. This ED medication further enhances muscle relaxation and blood flow to the penis. The metabolism or breaking down of Tadalafil occurs in the liver. The average elimination rate or half-life of Tadalafil is 17.5 hours. Elimination of the drug occurs in the kidney through feces and urine.
Tadalafil helps sexually stimulated ED patients achieve a firm erection by relaxing the muscles and enhancing blood flow in the penile region.
Tadalafil relaxes the bladder and prostate muscles and helps with urinating difficulties.
Tadalafil relaxes the blood vessels in the chest and treats the symptoms of PAH.
Consult a medical professional before taking the ED medication. The dosage and duration of treatment depend on the severity, cause, age, and underlying medical conditions.
It is available in various strengths. It is important to note that you should seek the advice of a specialist before changing your medication dosage.
The recommended dosage for treating BPH is 5 mg daily. Take the ED medication at the same time each day for maximum efficacy and consistency.
If you are taking Tadalafil for erectile dysfunction (ED) and benign prostatic hyperplasia (BPH), you should take one daily dose of 5 mg or the dosage prescribed by your doctor.
Individuals with PAH may take 40 mg of Tadalafil daily.
This PDE5 inhibitor might react with 285 drugs. These reactions can change the working of the medicine and increase the possibility of side effects.
Tadalafil is well tolerated, which indicates that it is safe and can be taken to a certain extent without causing adverse effects. However, improper medication use may result in risks and side effects.
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