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ArmodafinilAll Products

Armodafinil belongs to a class of drugs called the wakefulness-promoting agent that promotes alertness and wakefulness in people suffering from excessive daytime sleepiness. They act as powerful Nootropics, thus improving users' memory, concentration, and creativity. With an onset time of 30 minutes, It is an effective and advanced Nootropic that works for 12 to 15 hours.

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Legal Status

Australia (AU)- S4 (Prescription only)

USA- Schedule IV (Prescription only)

FDA approval Yes, In 2007
Habit-Forming Yes
Therapeutic Class Neuro CNS
Action Class Stimulant/ Drug for excessive sleepiness

What is Armodafinil?

It is a eugeroic medicine that helps to promote wakefulness. It treats excessive daytime sleepiness caused by obstructive sleep apnea, narcolepsy, and shift work disorder. In addition to its wakefulness-promoting effect, Armodafinil works as a cognitive enhancer (Nootropic), providing better brain functions.

Armodafinil Brand Name

The generic Armodafinil is available in several trade names that have the same potency and working mechanism. The common brands are:

How Does Armodafinil Work?

The Armodafinil mechanism of action localizes in the Central Nervous System. It restricts the Gamma-Aminobutyric Acid (GABA), a chemical in the brain that slows down brain functions or triggers sleepiness when available in high amounts. Armodafinil then promotes the neurotransmitters or brain chemicals such as dopamine, histamine, norepinephrine, and orexin. These neurotransmitters contribute to alertness and wakefulness promotion. The breakdown of the Nootropic occurs in the liver. Upon oral consumption, the Armodafinil Nootropic is readily absorbed in the body and starts working within 30 minutes. The peak drug concentration in the body reaches 2 hours. However, food can slow down the process by 2 to 4 hours.

Armodafinil's half-life, or the time the body takes to decrease the drug into half, is 12 to 15 hours. Excretion mainly occurs through the kidney as urine.


What Is Armodafinil Uses For?

Armodafinil are primarily prescribed for treating excessive daytime sleepiness or hypersomnia by promoting wakefulness during the daytime and improving sleep quality. It also helps to restore the natural wake-sleep pattern.

Other non-medical advantages of Armodafinil are:
  • Armodafinil for ADHD or Attention Deficit Hyperactivity Disorder provides an improvement in the symptoms.
  • Chronic fatigue syndrome.
  • It can be used as a secondary treatment for schizophrenia.
  • Improves jet lag.
  • Armodafinil for major depressive disorder is effective.

Benefits Of Armodafinil

  • It provides prolonged effectiveness.
  • It can be taken once daily, while other medications might require multiple dosing.
  • It acts fast within 30 minutes of consumption.
  • More efficient hence a lower dose can provide maximum benefit.
  • The medicine is safe for long-term use for up to 12 weeks without side effects (drug tolerability).


Armodafinil Dosage

It is available in various doses of 50mg, 150mg, 200mg, and 250mg. The standard or mostly prescribed dose is the Armodafinil 150mg tablet. However, your doctor might suggest the dosage and duration based on your medical and physical conditions.

For sleep disorders such as excessive daytime sleepiness, obstructive sleep apnea, and narcolepsy, the recommended dose is 150mg to 250mg daily in the morning. For shift work disorder, the recommended Armodafinil dose is 150mg which should be taken 30 to 1 hour before the work shift.

How To Take Armodafinil?

  • Take the pill orally with water.
  • Do not chew or crush the pill.
  • The best time to take Armodafinil is in the morning before 10 am.
  • Taking this medicine at least one hour before the night shift work is necessary.
  • The medicine can be taken with or without food. However, taking the Armodafinil pill on an empty stomach is preferable for immediate benefits.
  • Do not take this medicine late in the evening or before bedtime except for shift workers.
  • Do not take extra tablets if you miss a dose. Skip the missed dose and continue the regular dosing regime.

Factors That Affect The Efficacy Of Armodafinil

A few factors that might affect the working of the Nootropic are as follows.
  • Dosage : A higher dose might provide better efficacy compared to a lower dose of the medicine.
  • Metabolism : Individuals with poor or slow metabolism rates will take more time to experience the effectiveness of the medicine.
  • Age : The medicine might be less effective in older or aged consumers.


Some Warnings of Armodafinil

  • Taking Armodafinil with food will have minor interaction with the medicine absorption process in the body.
  • Do not consume Alcohol or other addictive substances with the Nootropic.
  • Patients with a history of psychiatric complications such as mania, depression, or psychosis (hallucination and delusions) should take prior medical consultation.
  • Bipolar disorder or patients with a risk of developing such disorder should undergo regular monitoring while consuming the Nootropic and consult their doctor.
  • Patients with cardiovascular or heart disease or high blood pressure should maintain caution.

Before taking Armodafinil

  • Prior consultation is mandatory for pregnant, nursing mothers, or females planning to conceive.
  • Do not drive or operate heavy machinery, as the medicine can cause drowsiness and dizziness.
  • Patients with a history of seizures or liver or kidney disease should consult a healthcare professional.
  • Individuals below 18 years are not recommended to take the pill without consulting a doctor.
  • Allergy patients must ensure they are not allergic to any medicine ingredients.
  • To avoid Armodafinil withdrawal, do not stop taking the Nootropic suddenly without talking to a doctor.

Drug interaction

Interactions of Armodafinil

This Nootropic reacts with 434 drugs. One should consult the doctor before taking any other medications, such as muscle relaxers, sleeping pills, narcotic medicine, etc., with Armodafinil. It is also important to note that taking any vitamins or herbal medicines with the Nootropic should be avoided. The list below provides the drugs (not a complete list) that can cause possible interactions with Armodafinil.

Major Interaction (16 drugs) Moderate Interaction (232 drugs)
Hydrocodone Albuterol
Belzutifan Buspirone
Citalopram Carisoprodol
Fentanyl Diazepam
Oxycodone Exemestane
Methadone Felodipine
Ranolazine Ketamine

Side Effects

Side Effects of Armodafinil

The common side effects below are mild and do not require immediate medical attention. However, if the symptoms are severe and persist longer, visit your nearest doctor.
  • Headache
  • Dizziness
  • Nausea
  • Difficulty sleeping
Seek immediate medical help if you experience any of the following symptoms:
  • Severe skin reaction
  • Breathing difficulty
  • Fever
  • Bleeding of the nose or gums
  • Chest pain
  • Hallucination or depression

The symptoms provided here are not a complete list of Armodafinil's possible side effects.

Medically reviewed by:
Last reviewed: 7th March 2023

frequently asked questions

Needs Answer? Find them here

Where to buy Armodafinil?
One should buy Armodafinil from a reliable pharmacy like Remedy Counter. This online pharmacy provides a hassle-free experience with discounted Armodafinil cost. Moreover, no prescription is required.
Is Armodafinil a controlled substance?
Yes, Armodafinil is a schedule IV drug.
How long does Armodafinil last?
The effectiveness of the medicine lasts for up to 15 hours.
Will Armodafinil show on a drug test?
Only specific tests for detection can verify the presence of the Nootropic in the system.
How long does Armodafinil take to kick in?
Armodafinil takes about 30 minutes after consumption to start working.
Is Armodafinil addictive?
Under proper medical guidance, the possibility of habit formation is low. However, individuals with a history of substance use disorder are most susceptible to dependence.
Does Armodafinil cause weight loss?
Studies show that upon six months of Armodafinil consumption, patients lost about 2.4kg of fats. As the Nootropic suppresses appetite, the consumer might lose weight.
Is Armodafinil Nootropic a narcotic?
No, Armodafinil is wakefulness and alertness-promoting non-narcotic medicine.
Can Armodafinil cause fatigue?
Studies show that Armodafinil treatment reduces chronic fatigue syndrome.
Does Armodafinil help depression?
Armodafinil provides mood-enhancing effects. Studies and Armodafinil reviews by consumers show an improvement in depression due to bipolar disorder.

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