Armodafinil belongs to a class of drugs called the wakefulness-promoting agent that promotes alertness and wakefulness in people suffering from excessive daytime sleepiness. They act as powerful Nootropics, thus improving users' memory, concentration, and creativity. With an onset time of 30 minutes, It is an effective and advanced Nootropic that works for 12 to 15 hours.
Overview
| Legal Status |
Australia (AU)- S4 (Prescription only) USA- Schedule IV (Prescription only) |
| FDA approval | Yes, In 2007 |
| Habit-Forming | Yes |
| Therapeutic Class | Neuro CNS |
| Action Class | Stimulant/ Drug for excessive sleepiness |
It is a eugeroic medicine that helps to promote wakefulness. It treats excessive daytime sleepiness caused by obstructive sleep apnea, narcolepsy, and shift work disorder. In addition to its wakefulness-promoting effect, Armodafinil works as a cognitive enhancer (Nootropic), providing better brain functions.
The Armodafinil mechanism of action localizes in the Central Nervous System. It restricts the Gamma-Aminobutyric Acid (GABA), a chemical in the brain that slows down brain functions or triggers sleepiness when available in high amounts. Armodafinil then promotes the neurotransmitters or brain chemicals such as dopamine, histamine, norepinephrine, and orexin. These neurotransmitters contribute to alertness and wakefulness promotion. The breakdown of the Nootropic occurs in the liver. Upon oral consumption, the Armodafinil Nootropic is readily absorbed in the body and starts working within 30 minutes. The peak drug concentration in the body reaches 2 hours. However, food can slow down the process by 2 to 4 hours.
Armodafinil's half-life, or the time the body takes to decrease the drug into half, is 12 to 15 hours. Excretion mainly occurs through the kidney as urine.
Uses
Armodafinil are primarily prescribed for treating excessive daytime sleepiness or hypersomnia by promoting wakefulness during the daytime and improving sleep quality. It also helps to restore the natural wake-sleep pattern.
Dosage
It is available in various doses of 50mg, 150mg, 200mg, and 250mg. The standard or mostly prescribed dose is the Armodafinil 150mg tablet. However, your doctor might suggest the dosage and duration based on your medical and physical conditions.
For sleep disorders such as excessive daytime sleepiness, obstructive sleep apnea, and narcolepsy, the recommended dose is 150mg to 250mg daily in the morning. For shift work disorder, the recommended Armodafinil dose is 150mg which should be taken 30 to 1 hour before the work shift.
Warning
Drug interaction
This Nootropic reacts with 434 drugs. One should consult the doctor before taking any other medications, such as muscle relaxers, sleeping pills, narcotic medicine, etc., with Armodafinil. It is also important to note that taking any vitamins or herbal medicines with the Nootropic should be avoided. The list below provides the drugs (not a complete list) that can cause possible interactions with Armodafinil.
| Major Interaction (16 drugs) | Moderate Interaction (232 drugs) |
|---|---|
| Hydrocodone | Albuterol |
| Belzutifan | Buspirone |
| Citalopram | Carisoprodol |
| Fentanyl | Diazepam |
| Oxycodone | Exemestane |
| Methadone | Felodipine |
| Ranolazine | Ketamine |
Side Effects
The symptoms provided here are not a complete list of Armodafinil's possible side effects.
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