Vardenafil: Brand name, uses, Interaction & precaution

Overview
Uses
Dosage
Warning
Drug Interactions
Side Effects

Overview

Legal Status	Australia (AU)- S4 (Prescription only) Canada- Prescription only UK- Prescription only USA- Prescription only
FDA approval	Yes, In 2003
Habit-Forming	No
Action Class	Phosphodiesterase (PDE) inhibitors

What is Vardenafil?

Vardenafil hydrochloride salt is an oral phosphodiesterase (PDE) inhibitor approved for erectile dysfunction in men. Impotence or ED occurs when men fail to get and maintain an erection firm enough for intercourse.

It is an effective and safe ED treatment option with potential benefits over current therapies. The ED pill increases blood flow into the penis to help restore the ability to get and sustain an erection.

Vardenafil Brand Name

Vardenafil generic is marketed under a variety of brand names.

The manufacturer assigns brand names, while generic names refer to the active ingredient.

The Vardenafil brands contain the same active ingredient and have comparable benefits and action mechanisms. Some of its popular brand drugs include

Vilitra pills
Levitra
Vivanza
Staxyn

How Does Vardenafil Hydrochloride Work?

After oral administration, it is broken down in the liver and passed out of the body with the help of the kidneys as urine and feces. The half-life of the ED pill is 4 to 5 hours, and it takes 20 to 30 minutes to start acting.

A person with erectile dysfunction does not get enough blood flow to their penis for a firm erection. The intake of Vardenafil enhances the release of nitric oxide (NO) in the presence of sexual stimulation. The NO further activates the enzyme guanylate cyclase, which increases the guanosine monophosphate (cGMP) level, leading to the relaxation of the blood vessels in the abdominal area. This helps increase the blood flow into the penis, thus helping achieve and maintain a firm erection.

Uses

What Is Generic Vardenafil Uses For?

Men with diabetes, high blood pressure, depression, or stress who take Vardenafil tablets have less trouble getting and keeping an erection. Additionally, it improves ED in men who have undergone a prostatectomy (prostate gland surgery).

Besides its prescription benefits, Vardenafil are an effective treatment for premature ejaculation.

Some other medical conditions that can be improved with Vardenafil are,

Raynaud’s phenomenon (lower blood flow to the fingers)
Pulmonary arterial hypertension (high blood pressure affecting the heart and lungs)
Chronic thromboembolic pulmonary hypertension (high blood pressure in the lungs' blood vessels).

Benefits Of Vardenafil

The long-term treatment with Vardenafil is safe because of its low risk of causing addiction and dependency.
It is more effective compared to other ED pills.
It is an affordable treatment option for erectile dysfunction.

Dosage

Vardenafil Dose

The dose prescribed by a doctor is determined by the patient's age, health factors, and the severity of the condition. It is available in two formulations: film-coated tablets and disintegration pills.

Film-coated tablets : These are pills with a thin coating on top. This coating can affect the tablet's appearance and mechanism of action.
Disintegrating Pills : These oral tablets dissolve in our mouth within seconds without needing water.

The film-coated vardenafil pills differ from their disintegrating counterparts; therefore, they should not be switched without consulting a physician. The Vardenafil dosage for erectile dysfunction should be taken once daily, about 20 to 60 minutes before intercourse.

How To Use Generic Vardenafil Pills?

Vardenafil is available as oral tablets and disintegrating pills. So, they must be administered accordingly. The oral medication should be swallowed with water, whereas the disintegrating pill should be placed on your tongue to dissolve.
It can be taken with or without food as directed by your physician.
Do not overdose on the ED pill to avoid facial flushing and headache.
The medication should be taken without being crushed or broken.
Taking the ED pill at the same time every day can help improve its benefits.
Sudden discontinuation of the medication is not advisable.

Factors That Affect The Efficacy Of Vardenafil Tablets

Factors that can affect the effectiveness of tablets include

Dosage :

The higher the dosage, the longer the medication's time of action.

Age :

The metabolism of a person slows down with age. Thus, such people take longer to break down the medication for it to start acting.

Lifestyle :

Certain lifestyle choices, such as smoking, lack of physical activity, and obesity, can increase the risk of erectile dysfunction and slow the drug's effects.

Psychological state :

Factors such as stress, childhood trauma, nervousness, depression, and anxiety can result in ED and the potency of the medication.

Overall Health :

Underlying health conditions such as diabetes and multiple sclerosis can also slow down the effectiveness of the ED pill.

You can also make your ED pill work better by the following tips.

Ensuring that treatment is right for you : Even though the ED pills work similarly, each has a different active ingredient. So, each medicine can have a different time of action, benefits, and side effects.
Food : Taking a meal rich in fat after the intake of the ED pill can make the medicine act slower than intended.
Give it time to work : Most ED pills do not work instantly. They take about 30 to 60 minutes to show positive results, which may go up to 3 hours in a few cases. So, give your medicine enough time to start acting.

Warning

Some Warning of Vardenafil

The intake of the ED pill in such conditions may cause an inability to differentiate between colors.
Vardenafil can cause seizures and should be taken cautiously in patients with an existing seizure disorder.
When consumed with alcohol, it can lower blood pressure, causing lightheadedness, flushing, dizziness, fainting, and palpitation.
People with leukemia (cancer) and sickle cell anemia are more likely to suffer from Priapism (painful erection exceeding 6 hours). It can result in permanent potency loss along with damage to the penile tissue.
Do not take Vardenafil tablets with pomelo, grapefruit, and pomegranate juices.

When To Visit A Doctor?

Consult a physician if your ED is caused by high blood pressure and diabetes.
Psychological causes of erectile dysfunction, such as anxiety, stress, and depression, should be evaluated by a physician.
Occasional erectile dysfunction does not require medical attention; however, men who experience ED frequently should consult a physician.
When an erection is delayed or premature, getting the proper treatment is essential.

Before taking

Before taking Vardenafil, check with your doctor or pharmacist if you are allergic to its ingredients.
People with health issues such as angulation, cavernosal fibrosis, or Peyronie's disease that affect the shape of the penis should take the ED pill after consulting a doctor.
The ED pill is not for people below 18 years old.
Individuals with high blood pressure, cholesterol, sickle cell anemia, irregular heartbeat, stomach ulcers, and heart and kidney disorders should take the ED pill under the supervision of a physician.
The disintegrating tablets may contain artificial sweeteners such as aspartame. Thus, its use in diabetic patients should be closely monitored.
Before any dental procedure and surgery, inform your doctor about taking the ED pill.

Facts & Myths

The Vidalista pill works only in the presence of sexual stimulation. The ED pill will not work if you are not naturally aroused.
The ED pill does not affect sperm count.
Vidalista does not affect the individual's sexual desire.
It is a temporary solution; once the medication's effect wears off, your ability to achieve a hard erection will diminish.
Vidalista dosage does not affect penis length.
It does not protect against sexually transmitted diseases.
Vardenafil is not recommended for women unless prescribed by a physician for PAH.

Drug interaction

A "drug interaction" is a reaction between two or more compounds and medications. It may change how your medicine works, increasing or decreasing the possibility of experiencing side effects.

When taken with nitrates, Vardenafil may cause a severe fall in your blood pressure level, leading to fainting, dizziness, and stroke. It can also cause hypertension (high blood pressure) when taken with alpha-blockers, such as doxazosin and tamsulosin (used to treat enlarged prostate).

The rate of metabolism of Vardenafil can increase when taken with Abatacept, Daunorubicin, Efavirenz, Haloperidol, Ivacaftor, and Methimazole. It can decrease when the ED pill is administered with Acetaminophen, Nicardipine, Zimelidine, Hydrocortisone, Triclabendazole, Rilpivirine, Oxycodone, and Letermovir.

Certain medications such as Abametapir, Clarithromycin, Daclatasvir, Indinavir, and Lopinavir can increase the serum concentration of Vardenafil. The risk of QTc prolongation ( time between heartbeats) can increase when the ED pill is taken with Acrivastine, Lumefantrine, Cetirizine, Hydroxyzine, Entrectinib, Macimorelin, and Olodaterol. it, however, does not indicate all the possible drug interactions of Vardenafil. Such interactions can be managed by:

Avoiding the use of disintegrating tablets in beginners.
Start with a lower dose of the Vardenafil pill to lower the risk of getting low blood pressure.
Inform your doctor if you are undergoing any treatments.

Side Effects

Side Effects of Vardenafil

Vardenafil tablet is a well-tolerated medication, which refers to the extent to which the body can tolerate a side effect without developing symptoms. The use of Vardenafil is associated with a decrease in hearing, often accompanied by dizziness and drowsiness. It can also result in headaches, blurry vision, nausea, vomiting, agitation, palpitation, stomach upset, and flu-like symptoms.

It is advised to consult a doctor if you experience ringing in the ear, difficulty swallowing or breathing, hoarseness, rashes, and hives.

Medically reviewed by:

Dr. Uche Ogbuagu (Medical Researcher)

Last reviewed: 7th March 2023

frequently asked questions

Needs Answer? Find them here

Can I take 40 mg of Vardenafil?

Yes, Vardenafil (Vilitra 40 mg) can be taken once a day to treat erectile dysfunction.

What does the medication Vardenafil hydrochloride cost in the USA?

The cost of the Vardenafil tablet is about $1.2 per pill in the USA.

Does Vardenafil expire?

Yes, like most pharmaceutical drugs, Vardenafil has a shelf life of about two years from the manufacturing date.

How long do the effects of Vardenafil last?

The effect of Vardenafil lasts for 4 to 5 hours.

How can I make Vardenafil more effective?

Take the pill as directed by your physician to enjoy its effectiveness. It is an oral pill and should be taken by mouth without breaking. Avoid overdosing and administering the medication with other medication to avoid side effects.

Can I take Vardenafil daily?

Vardenafil has a lower risk of addiction and dependency, thus making its long-term use safe.

Can a woman take Vardenafil?

The use of the ED pill is not for women. Its effect during breastfeeding and pregnancy is not known.

Can you split Vardenafil?

The tablet should not be broken, split, or crushed before use.

What happens if you take too much Vardenafil?

Overdosing on Vardenafil can cause priapism, a condition where an erection lasts for several hours.

Does Vardenafil affect sperm?

Vardenafil does not affect semen characteristics or sperm count in men.

What other pills have Vardenafil?

One common Vardenafil brand is Vilitra.

How long does Vardenafil stay in your system?

The elimination half-life of Vardenafil is 4 to 5 hours. Therefore it stays in the system for about 24 hours.

Where can I get Vardenafil?

Vardenafil is available in local pharmacies with a valid prescription. It can also be bought from online pharmacies.

Why is Vardenafil so expensive?

One reason for Vardenafil being so expensive is that its cost is not covered by numerous medicare and insurance plans. It can, however, be bought online at a discounted price of $1.2 per pill.

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