Etadol 100 mg plays an important role in managing moderate to severe pain. Also available in extended-release formula (Etadol 100 ER), a single dose of the analgesic provides 12 hours of pain relief.
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What is Etadol100mg?
Etadol 100 is a popular Tapentadol brand approved by the FDA for chronic pain. It is a centrally-acting opioid analgesic with a dual mechanism of action known to produce effective relief from pain with a lower potential for abuse. Etadol 100mg is marketed as having better tolerability than other opioid analgesics with a faster onset of action of 30 minutes.
Etadol 100 mg Pill Identifier
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Structure: Round tablet
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Color: Sunset Yellow
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List of Ingredients: Tapentadol Hydrochloride 100mg is the active compound, whereas the other ingredients include Microcrystalline Cellulose, Polyvinylpyrrolidone, Povidone K 30 USP, Croscarmellose sodium, Colloidal Silicon Dioxide, and Magnesium Stearate.
Working Mechanism Of Etadol Tablets
Etadol combines two mechanisms of action in a single molecule-
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μ-opioid receptor (MOR)- Etadol activates the opioid receptor (MOR) that prevents the release of neurotransmitters causing pain.
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Noradrenaline reuptake inhibition (NRI)- It blocks the reuptake of the Noradrenaline hormone, thus allowing more Noradrenaline to stay active. This hormone plays a key role in reducing the severity of body pain.
The Etadol 100mg is broken down in the liver and is eliminated from the system through the kidney. The elimination half-life (the time taken by medication to reduce to half) is 4 hours, and it takes about 24 to 48 hours for the body to eliminate Etadol from the system.
Uses Of Etadol 100 tablet
The therapeutic use of prescription Tapentadol or Etadol 100mg tablet is as a pain-relieving drug effective for arthritis, injury, and gout (a form of arthritis). It is also effective for neuropathic and phantom pain (from surgically removing the limb).
Off-Label Uses
Beyond its prescription uses, Etadol 100 mg can be effective as a treatment option for -
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Fibromyalgia - It is a condition causing musculoskeletal pain. The use of Etadol 100 tablets can help get relief the pain associated with this condition.
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Postoperative pain- Etadol 100 mg demonstrates great potency in managing moderate to severe postoperative pain.
Benefits
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Etadol 100 mg has a quick onset of action of 30 minutes.
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It has a lower risk of side effects, making it a safer analgesic option.
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Etadol is an effective therapeutic option in cases where other pain medication fails to give a promising result.
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Most Medicare and insurance policies cover the cost of Etadol 100 mg.
Etadol 100 MG Dosage
Etadol 100mg is an extended-release (ER) tablet. These are medications formulated to release slowly over time, thus providing long-term benefits in lowering body pain. The standard dose of Etadol is 100mg and should be taken only for chronic pain. The dose of the pain medication is twice daily at an interval of 12 hours.
The maximum dose of Etadol is 500mg which should not be exceeded without consulting a doctor. Overdosing on Etadol can cause severe health risks, including confusion, shallow breathing, nausea, and vomiting.
For missed dosage, skipping it and continuing with your regular schedule is advisable.
DO NOT TAKE AN EXTRA PILL TO MAKE UP FOR YOUR MISSED ETADOL ER DOSAGE.
How To Use Etadol 100 mg
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Etadol ER 100 mg is an oral tablet and should be taken by mouth.
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It should be taken as a whole with water.
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Dosage adjustments of up to 8 hours are recommended for people with liver disorders.
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Taking the medication at the same time every day increases its effectiveness.
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Etadol 100 dosage can be taken with or without food.
Storage
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Keep them at room temperature, away from sunlight and moisture.
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They should not be at a reachable height for your pets and children.
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Storing them in their original packaging is advisable.
Warning
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Respiratory depression in individuals can result from overdosing on this medication.
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Etadol 100mg can worsen the case of diarrhea in people with a stomach infection.
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Take the drug after consulting a doctor if you suffer from gastrointestinal obstruction, constipation, and inflammatory bowel disease.
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Consumption of alcohol with Etadol 100 mg is not advisable.
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A higher dose of Etadol can cause hypotension (reduction of blood pressure).
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The analgesic can cause spasms and increase the biliary tract pressure, thus should be taken with caution.
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Intravenous administration of Etadol can reduce the flow of oxygen to the blood (cerebral hypoxia) and cause a decrease in blood pressure by vasodilation.
Before Taking
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Etadol can cause dizziness and drowsiness, making driving or using machinery unsafe.
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People below 18 and above 65 years should consult a doctor before use.
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It is a category C pregnancy drug and should be taken by breastfeeding and pregnant women.
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Long-term use of opioid pain medication can reduce fertility.
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People with kidney, liver, and heart disorders should consult a doctor before taking Etadol 100 mg.
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It can cause respiratory depression and should be avoided by people with asthma and COPD (air passage blockage).
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Crushing and breaking the Etadol ER 100 mg tablet can cause rapid release of the compound in the system resulting in severe health issues.
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The administration of the Etadol tablet should be avoided for 14 days after taking MAO inhibitor antidepressants.
Alternative Etadol 100mg Dosage
The Etadol alternatives you can choose from are listed below. They are formulated with similar active compounds showing similar benefits and mechanisms of action.
Drug Interaction
Drug interaction is a condition where two or more medications interact with each other to lower their effectiveness and benefits.
372 medications are known to interact with Etadol 100 mg, a few of which are listed below (not a complete list).
Moderate Interaction |
Major Interaction |
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188 moderate drug interactions known |
183 major drug interactions known |
Arformoterol |
Acetylcarbromal |
Brivaracetam |
Bupropion |
Clidinium |
Clomipramine |
Diphenhydramine |
Dolasetron |
Epinephrine |
Escitalopram |
Formoterol |
Frovatriptan |
Ginkgo |
Granisetron |
Hyoscyamine |
Hydromorphone |
Indacaterol |
Imipramine |
Ketamine |
Metrizamide |
Methsuximide |
Naltrexone |
Rotigotine |
Orphenadrine |
Side Effects
Etadol 100mgl is a highly tolerable medication indicating that our body can withstand the drug without showing signs of side effects. The risk of Etadol 100 side effects is higher
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when you increase the dosage
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If you are taking Etadol for the first time
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In elderly people.
Some common side effects of Etadol are nausea, vomiting, constipation, nausea, headache, dizziness, and drowsiness. People with allergic reactions resulting in rash, mouth sores, and blisters should immediately discontinue the medication.
Consult a doctor if you have-
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Shallow or noisy breathing
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Lightheadedness
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Severe dizziness or drowsiness
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Hallucination
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Muscle stiffness
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Problems with speech
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Loss of coordination
In rare cases, this opioid medication can cause an increase in the serotonin level, causing serotonin syndrome.
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Reviews For Etadol 100 MG
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It takes 30 minutes for Etadol to start acting.